Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review

Isatin is a heterocyclic molecule that belongs to one of the most important classes organic compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently attracted lot attention in medicinal chemistry. itself, shows various biological activities such antiviral, anticancer, antimicrobial, anti-inflammatory, analgesic, antioxidant, anticonvulsant. Bis- containing moiety been possess wide spectrum pharmacological activities. This review offers up-to-date information on active bis-Schiff bases, which would include anticonvulsant, analgesic These observations can lead new molecular modifications result with more desirable properties